Figure 4
Spatial topography and age-related regression analysis where relevant in the (A–C) outer nuclear layer with Henle’s fibre layer (ONL+HFL), (D–F) photoreceptor inner-segment and outer-segment layer (IS/OS), and (G–I) retinal pigment epithelium (RPE), using location-specific cluster analysis. For each layer, the (A,D,G) spatial cluster patterns (in right eye format), (B,E,H) corresponding plots of cluster thickness versus groups, i.e. age interval cohorts or singular grouping using the whole cohort, and (C,F) corresponding age-correction regression functions, vertex ages), and slopes as derived after the vertex age are presented. All slopes were significantly different from zero (p < 0.05). Presentation as in Fig. 2.
