Figure 1 | Scientific Reports

Figure 1

From: Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein

Figure 1

X-ray structure of PTPN3-PDZ bound to PBM-HBc. (a) Superimposition of the structures of PTPN3-PDZ bound to PBM-HBc (PDB ID: 6T36, light grey) and PBM-HPV16E6 (PDB ID: 6HKS, light green). (b) Representation of the density of the peptide in the binding groove of the PDZ domain. (c) Detailed views of the PTPN3-PDZ bound to PBM-HBc. Important residues are shown as sticks in CPK colors, molecules of water are represented as red spheres, and intermolecular H-bonds and polar contacts are shown as yellow dashed lines. Black dashed lines show the H-bond pairing with the β2-strand.

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