Figure 6 | Scientific Reports

Figure 6

From: Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein

Figure 6

Schematic model of the multiple PBM-mediated interactions of HBc with PTPN3 and other PDZ-containing proteins. The model illustrates the competition of HBc with PTPN3 cellular ligands (CNP, PTB). The subsequent complex formed between the two proteins could allow the dephosphorylation of HBc by PTPN3, potentially affecting capsid stability. HBc could also target and alter functions of other cellular PDZ-containing proteins (proteins X, Y, Z).

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