Table 1 Peripapillary retinal nerve fiber layer (pRNFL) thickness in VHL eyes with or without RH and healthy controls.

From: Structural and microvascular changes of the peripapillary retinal nerve fiber layer in Von Hippel–Lindau disease: an OCT and OCT angiography study

pRNFL thickness (μm: mean ± SD)

VHL w/out RHs (71 eyes)

Healthy controls (56 eyes)

VHL with RH

(38 eyes)

VHL w/out RH

vs controls

p-value

VHL with RH vs VHL w/out RHs

p-value

VHL with RH vs controls

p-value

Mean pRNFL

100.7 ± 13.4

104.2 ± 7.4

103.5 ± 9.9

0.0172

0.0201

0.7421

T-pRNFL

66.2 ± 11.1

71.7 ± 14.2

73.3 ± 9.0

0.0454

0.0002

0.5334

TS-pRNFL

134.9 ± 18.3

144.6 ± 16.3

147.4 ± 18.4

0.0127

0.0005

0.6526

NS-pRNFL

116.1 ± 31.7

112.4 ± 19.7

117.2 ± 27.9

0.6076

0.6338

0.4462

N-pRNFL

78.5 ± 18.8

81.9 ± 13.4

76.3 ± 15.6

0.3735

0.7145

0.1471

NI-pRNFL

119.3 ± 26.1

121.4 ± 17.8

111.2 ± 14.5

0.6727

0.0880

0.0226

TI-pRNFL

145.9 ± 22.4

150.9 ± 19.0

152.2 ± 20.9

0.2036

0.0083

0.7188

PMB

51.1 ± 8.8

52.9 ± 7.4

55.1 ± 7.1

0.3429

0.0010

0.1714

  1. N-pRNFL, nasal sector-peripapillary Retinal Nerve Fiber Layer; NI-pRNFL, nasal-inferior sector-peripapillary Retinal Nerve Fiber Layer; NS-pRNFL, nasal-superior sector-peripapillary Retinal Nerve Fiber Layer; PMB, papillo-macular bundle; RH, retinal hemangioblastomas; T-pRNFL, temporal sector-peripapillary Retinal Nerve Fiber Layer; TI-pRNFL, temporal-inferior sector-peripapillary Retinal Nerve Fiber Layer; TS-pRNFL, temporal-superior sector-peripapillary Retinal Nerve Fiber Layer; VHL, Von Hippel Lindau disease; w/out, without.
  2. Significant p value in bold.