Figure 1
From: A novel human ex vivo skin model to study early local responses to burn injuries
Experimental setup for the ex vivo skin model for burn injury and inflammation. (a) The experimental procedure included the immediate transfer of the fresh abdominal skin explants to the laboratory, creation of a burn injury or intradermal injection of LPS or NaCl, collecting punch biopsies and molecular and histological analyses. Representative pictures of (b) a burn injury (right field) compared with a healthy, blank site (left), (c) the intradermal injection of LPS (inflammation; red circles in (a)) or NaCl (control for injection trauma; open circles in (a)), (d) sampling of biopsies and (e) the skin explant in the climate chamber.
