Figure 2

The correlation of the Siglec-15 and PD-L1 expression in our cohort (A tumor cells, B intratumoral macrophages, C peritumoral macrophages). In the majority of the patients (37 samples) tumor cells were negative for Siglec-15 and PD-L1. Larger numbers of samples had Siglec-15- and PD-L1-positive macrophages in comparison to tumor cells. With regard to the expression on peritumoral macrophages, the number of Siglec-15-positive samples (n = 24) was greater than the number PD-L1-positive samples (n = 16).