Table 2 Results of the univariate Cox survival analyses.

From: Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients

Factor

Hazard ratio (95%CI)

p value

Age ≥ 70

1.636 (0.782–3.426)

0.192

Molecular subgroup (GCB type vs Non-GCB type)

0.891 (0.359–2.213)

0.804

MSKCC score (class 3 vs class 1 and 2)

1.049 (0.479–2.295)

0.905

Siglec-15 positive tumor cells

1.241 (0.570–2.699)

0.586

Siglec-15 positive intratumoral macrophages

1.713 (0.783–3.748)

0.178

Siglec-15 positive peritumoral macrophages

0.404 (0.175–0.933)

0.0339

PD-L1 positive tumor cells

0.373 (0.149–0.931)

0.0347

PD-L1 positive intratumoral macrophages

1.369 (0.666–2.817)

0.393

PD-L1 positive peritumoral macrophages

0.585 (0.245–1.398)

0.227

Rituximab

0.999 (0.464–2.154)

0.999

High-dose methotrexate-based chemotherapy

0.417 (0.183–0.950)

0.0373

  1. CI, confidence interval; GCB, germinal center B-cell; MSKCC, Memorial Sloan Kettering Cancer Center.