Figure 1 | Scientific Reports

Figure 1

From: PDGFRα mediated survival of myofibroblasts inhibit satellite cell proliferation during aberrant regeneration of lacerated skeletal muscle

Figure 1

Pathology of lacerated skeletal muscle. (A) Histological analysis of gastrocnemius muscle post injury at different time intervals. H&E staining shows the trend of myofiber regeneration and cell infiltration. Box1—infiltrated immune cells; Box2—dedifferentiated muscle fibres (top panel). Masson’s trichrome staining of the sections. Results reveal heavy deposition of collagen indicated by the blue stain (bottom panel). (B) The collagen proportionate area (CPA) was quantified on the basis of morphometric analyses of 21 fields (10× magnification) of each time point using the ImageJ software. Data were presented as mean ± SEM.

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