Figure 1 | Scientific Reports

Figure 1

From: Lipid droplet biogenesis and COX-2 pathway activation are triggered by Barrett’s esophagus and adenocarcinoma, but not esophageal squamous cell carcinoma risk factors

Figure 1

Perilipin-2 expression pattern in esophageal samples. (A) Representative immunohistochemistry micrographs of esophageal samples from non-obese individuals (NOE; n = 10), obese individuals (OE; n = 21), Barrett’s esophagus (BE; n = 30), esophageal adenocarcinoma (EAC; n = 64) and esophageal squamous cell carcinoma (ESCC; n = 25) patients stained for Perilipin-2. Colon adenocarcinoma (CAC) samples were used as positive control for Perilipin-2 staining. (B) Graphical representation of the esophageal samples’ Perilipin-2 staining score. (C) PLIN-2 mRNA expression evaluated in 88 EAC and 95 ESCC samples, from patients whose data is available at TCGA database. Gene expression pattern is evaluated from RNA-seq data, and represented as RSEM-1 units *p < 0.05; **p < 0.005; ***p < 0.0005.

Back to article page