Table 4 Univariate and multivariate analysis of factors associated with seroconversion of hepatitis A vaccination in both groups (n = 93).

From: A randomized controlled trial of comparative effectiveness between the 2 dose and 3 dose regimens of hepatitis a vaccine in kidney transplant recipients

Factors

Univariate analysis

Multivariate analysis

OR (95%CI)

p value

OR (95%CI)

p value

Age (years)

1.004 (0.964–1.046)

0.853

0.991 (0.941–1.044)

0.734

Gender

Male

1.042 (0.461–2.351)

0.922

0.919 (0.311–2.713)

0.905

Female

1.00 (reference)

   

Type of transplantation

Living donor kidney transplant

1.635 (0.714–3.741)

0.245

1.749 (0.576–5.313)

0.324

Deceased donor kidney transplant

1.00 (reference)

   

Time post transplantation (months)

1.004 (0.996–1.012)

0.315

1.007 (0.993–1.020)

0.317

eGFR (1 mL/min/1.73 m2)

1.033 (1.011–1.056)

0.033

1.033 (1.005–1.063)

0.021

Hemoglobin

1.204 (0.963–1.507)

0.104

1.072 (0.783–1.468)

0.663

White blood cells count (cells/µL)

1.000 (1.000–1.000)

0.911

1.000 (1.000–1.000)

0.799

Lymphocyte count (cells/ µL)

1.000 (1.000–1.001)

0.263

1.000 (0.999–1.001)

0.975

Albumin (g/dL)

4.953 (1.235–19.872)

0.024

10.601 (1.557–72.164)

0.016

Immunosuppressive regimen

Tacrolimus + mycophenolic acid

1.00 (reference)

   

Low intensity regimens

3.939 (1.620–9.580)

0.002

4.552 (1.310–15.816)

0.017

Prednisolone (mg/day)

0.892 (0.782–1.018)

0.89

0.972 (0.850–1.111)

0.677

Vaccine dose

2-dose

1.00 (reference)

   

3-dose

1.136 (0.485–2.657)

0.769

0.944 (0.331–2.693)

0.914

  1. eGFR; estimated glomerular filtration rate by CKD-EPI.