Table 6 Diagnostic performance of serum models for severe drug-induced liver injury.

From: Increased red cell distribution width predicts severity of drug-induced liver injury: a retrospective study

Variables

AUROC

(95% CI)

Cut-off

Se (%)

Sp (%)

Correct classified (%)

RPR

0.527

0.419–0.635

0.073

58.3

52.3

53.0

AAR

0.633

0.537–0.728

0.599

86.1

41.4

51.2

RLR

0.714

0.620–0.807

10.227

66.7

71.1

70.1

RDW

0.855

0.793–0.917

14.650

86.1

73.4

76.2

TBA

0.905

0.860–0.950

45.850

100

74.2

79.3

Comparison of AUROC

      

TBA and RDW

P > 0.05

     

RDW and RLR

P < 0.05

     

RLR and AAR

P > 0.05

     

AAR and RPR

P > 0.05

     

RLR and RPR

P < 0.05

     
  1. The bold values were considered statistically significant (P < 0.05). Se, sensitivity; Sp, specificity.
  2. Cut-offs were established by maximizing the sum of sensitivity and specificity.
  3. AUROC area under the receiver operating characteristic curve, 95% CI 95% confidence interval.
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