Figure 6 | Scientific Reports

Figure 6

From: Immune modulation resulting from MR-guided high intensity focused ultrasound in a model of murine breast cancer

Figure 6

HIFU upregulates inflammatory cytokines and leukocyte signaling chemokines. (A) Heatmap visualization of Z-scores of leukocyte chemokines and cytokines for each treatment cohort. FPKM values for each cohort for (B) Cxcl9 and (C) Cxcl10. Data are expressed as mean ± SD. *p < 0.05, **p < 0.01 (ordinary one-way ANOVA with Tukey correction for multiple hypotheses). Time points are: 1-week post ablation for all cohorts that received thermal ablation, and 24 h post HIFU for cohorts that received mechanical HIFU. The heatmap was created in R Studio v1.2.5001 (https://rstudio.com).

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