Figure 4

Expression type cluster analysis for ICM organoids. (a) 24 h old ICM organoids; (b) 48 h old ICM organoids. Black indicates the presence of an expression type, white indicates its absence, respectively. Shown are slices through the ICM organoids at cartesian origin. Expression type compositions in dependence of the relative distance to the ICM organoid centre. Cells are sorted according to their distance to the ICM organoid centre of mass and binned into 10 groups. Points indicate the average proportion of a cell fate type for the 10 bins, the bars denote the standard deviation.