Figure 1

Heatmap of the relative abundance of the representative microbiota at first and second collections. Cervicovaginal microbiota were collected from 41 patients with CIN and identified by 16S rRNA V3/4 sequencing. First collection included before surgery and observation 1 described in figure. Color gradation indicates the relative abundance of microbiota. The scale of color gradation is indicated at the bottom. The number of microbial species qualified by the observed species richness (Sobs) is indicated as α-diversity in each specimen. Heatmap was drawn by Microsoft Excel.