Figure 3

Summary of regression for cell-type agnostic approach. (A) Volcano plot of DEGs identified after adjusting for cell composition. Positive log fold change corresponds to increased expression in ethanol-treated organoids. (B) Results from pathway enrichment analysis of genes found to be nominally overexpressed (red) and underexpressed (blue) following ethanol treatment. Overlap indicated the percentage of DEGs found in gene list that comprise that pathway.