Table 2 Correlation between mutated pathways and clinical characteristics.
Pathway | MAPK/ERK | DNA repair | WNT | PI3K | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
wt | mut | P-value | wt | mut | P-value | wt | mut | P-value | wt | mut | P-value | |
Histological type | ||||||||||||
pap/col | 10 | 7 | 12 | 5 | 13 | 4 | 14 | 3 | ||||
sol/muc | 10 | 0 | 0.026 | 7 | 3 | 1.000 | 8 | 2 | 1.000 | 7 | 3 | 0.638 |
Tumor stage | ||||||||||||
I-II-III | 15 | 6 | 15 | 6 | 16 | 5 | 15 | 6 | ||||
IVa-IVb | 5 | 1 | 1.000 | 4 | 2 | 1.000 | 5 | 1 | 1.000 | 6 | 0 | 0.284 |
Recurrence | ||||||||||||
No | 8 | 4 | 9 | 3 | 7 | 5 | 9 | 3 | ||||
Yes | 12 | 3 | 0.662 | 10 | 5 | 0.696 | 14 | 1 | 0.060 | 12 | 3 | 1.000 |
Patient status | ||||||||||||
Alive | 8 | 2 | 6 | 4 | 7 | 3 | 7 | 3 | ||||
dod | 8 | 1 | 8 | 1 | 9 | 0 | 8 | 1 | ||||
doc | 4 | 4 | 0.163 | 5 | 3 | 0.327 | 5 | 3 | 0.135 | 6 | 2 | 0.598 |
Tobacco | ||||||||||||
No | 10 | 3 | 9 | 4 | 10 | 3 | 11 | 2 | ||||
Yes | 7 | 4 | 0.659 | 8 | 3 | 1.000 | 8 | 3 | 1.000 | 8 | 3 | 0.630 |
