Table 1 Clinical and imaging characteristics, and immunostaining findings.

From: Subtype-dependent difference of glucose transporter 1 and hexokinase II expression in craniopharyngioma: an immunohistochemical study

 

Total, n = 29 (%)

ACP, n = 18 (%)

PCP, n = 11 (%)

p value

Age

0–19

4 (13.8)

4 (22.2)

0 (0.0)

 

20–39

6 (20.7)

4 (22.2)

2 (18.2)

 

40–59

12 (41.4)

8 (44.4)

4 (36.4)

 

60–79

7 (24.1)

2 (11.1)

5 (45.5)

 

Sex

M

15 (51.7)

7 (38.9)

8 (72.7)

0.128

F

14 (48.3)

11 (61.1)

3 (27.3)

 

Size

Median

34.8

37.5

28.4

0.105

IQR

23.6–41

27.1–44.7

22.9–37.3

 

Cyst formation

+ 

17 (58.6)

13 (72.2)

4 (36.4)

0.13

12 (41.4)

5 (27.8)

7 (63.6)

 

Calcification

+ 

17 (58.6)

17 (94.4)

0 (0.0)

 < 0.01

12 (41.4)

1 (5.6)

11 (100)

 

Approach

Nasal

19 (65.5)

12 (66.7)

7 (63.6)

1

Craniotomy

10 (34.5)

6 (33.3)

4 (36.4)

 

Past surgery

Initial surgery

26 (89.7)

16 (88.9)

10 (90.9)

1

Recurrent tumor

3 (10.3)

2 (11.1)

1 (9.1)

 

Removal extent

Median

95

95

95

0.98

IQR

90–100

90–100

92.5–100

 

Immunostaining

GLUT-1

 Positive

13 (44.8)

4 (22.2)

9 (81.8)

0.003

 Negative

16 (55.2)

14 (77.8)

2 (18.2)

 

HK-II

 Positive

10 (34.5)

2 (11.1)

8 (72.7)

0.001

 Negative

19 (65.5)

16 (88.9)

3 (27.3)

 

BRAF V600E

 Positive

10 (34.5)

0 (0.0)

10 (90.9)

 < 0.001

 Negative

19 (65.5)

18 (100)

1 (9.1)

 

Nuclear expression of beta-catenin

 Observed

18 (62.1)

18 (100)

0 (0.0)

 < 0.001

 Not observed

11 (37.9)

0 (0.0)

11 (100)