Table 1 Comparison of response metrics for efferent-mediated fast and slow excitation among different vertebrates.

From: The mammalian efferent vestibular system utilizes cholinergic mechanisms to excite primary vestibular afferents

Response metric

Mouse (this study)

Monkey2

Chinchilla13

Cat*12

Turtle*17,18

Fast Amp (spikes/s)

3–15 (0–72)

3.8–65.7

7.6–43.9

10–60

35–46

Slow Amp (spikes/s)

9.1–19 (3–43)

5.3–36.3

8.2–21.0

20–100

16–18

Fast Dur (s)

5–6

5–6

5–6

0.3–0.5

1.25–10

Slow Dur (s)

34–44

25–30

30–40

70–85

145

  1. The range of mean response amplitudes (Amp) and durations (Dur) are provided for several mammalian species and turtle. Efferent-mediated response metrics from regular and irregular afferents have been pooled to generate the range except for cat and turtle where data were only available for irregular afferents (*). Number in parentheses for mouse are the ranges of response amplitudes taken from individual units. Amp and Dur measurements were taken from average response histograms generated with different efferents stimuli—Mouse, squirrel monkey, and chinchilla: 1–12 shock trains (333 shocks/s for 5 s) repeated every 60–75 s; Cat: 64 shock trains with each train (200 shock/s for 400 ms) presented at 1.5 s intervals; Turtle, 10–25 shock trains (200 shocks/s for 100 ms) or a single shock train (100 shock/s for 10 s). Longer response durations in cat and turtle are attributed to the length of the efferent stimulus. References for each animal are shown as superscripts.
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