Table 1 Patient characteristics by sample groups.
From: A novel simple risk model to predict the prognosis of patients with paraquat poisoning
Characteristics | Aggregate | Training | Test | Validation_time | Validation_site | P_value |
|---|---|---|---|---|---|---|
Total | 1199 | 609 | 304 | 207 | 79 | |
Inhos_death n (%) | 454 (37.9) | 247 (40.6) | 117 (38.5) | 87 (42.0) | 3 (3.8) | < 0.0001 |
Female n (%) | 599 (50.0) | 297 (48.8) | 172 (56.6) | 93 (44.9) | 37 (46.8) | 0.0444 |
Age Mean (std) median (q1, q3) | 35.1 (16.4) 34 (23, 47) | 34.7 (16.5) 34 (23, 46) | 34 (16.2) 30.5 (23, 46) | 36.1 (17.2) 34 (25, 48) | 40.1 (12.8) 40 (29, 48) | 0.0104 |
Age_lt_50 n (%) | 963 (80.3) | 495 (81.3) | 246 (80.9) | 159 (76.8) | 63 (79.7) | 0.5614 |
Age_ge_50 n (%) | 236 (19.7) | 114 (18.7) | 58 (19.1) | 48 (23.2) | 16 (20.3) | 0.5614 |
ALT1 Mean (std) median (q1, q3) | 46.8 (114.6) 18 (12, 33) | 46.8 (102.2) 18 (12, 34) | 40.2 (81.1) 16 (12, 30.5) | 62.1 (187.4) 19 (12, 41) | 32 (32.5) 20 (13, 32) | 0.4286 |
ALT1_lt_100 | 1073 (89.5) | 546 (89.7) | 274 (90.1) | 179 (86.5) | 74 (93.7) | 0.3053 |
ALT1_ge_100 | 126 (10.5) | 63 (10.3) | 30 (9.9) | 28 (13.5) | 5 (6.3) | 0.3053 |
AST1 | 57.1 (139) 23 (17, 39) | 58.9 (146) 23 (18, 41) | 53.3 (117.6) 23 (17, 37.5) | 64.7 (168.3) 23.2 (18, 41) | 38.3 (39.3) 22 (17, 32) | 0.3409 |
AST1_lt_60 | 982 (81.9) | 498 (81.8) | 249 (81.9) | 170 (82.1) | 65 (82.3) | 0.9992 |
AST1_ge_60 | 217 (18.1) | 111 (18.2) | 55 (18.1) | 37 (17.9) | 14 (17.7) | 0.9992 |
BUN1 | 6.8 (5.8) 5.2 (4, 7.4) | 6.8 (5.5) 5.4 (4, 7.7) | 6.7 (5.5) 5 (3.9, 7.3) | 7.1 (7.2) 5.2 (4, 7.3) | 6.1 (5.4) 4.9 (4.1, 6.5) | 0.3161 |
BUN1_lt_10 | 1045 (87.2) | 530 (87.0) | 259 (85.2) | 180 (87.0) | 76 (96.2) | 0.0774 |
BUN1_ge_10 | 154 (12.8) | 79 (13.0) | 45 (14.8) | 27 (13.0) | 3 (3.8) | 0.0774 |
CK_MB1 | 29.4 (38.6) 20.2 (12.9, 33.6) | 31 (39.6) 21 (13.6, 36) | 31.3 (40.3) 20.9 (13.8, 32.7) | 28.6 (37.7) 19.1 (12.3, 33.3) | 12.1 (14) 3.8 (2, 25.5) | < 0.0001 |
CK_MB1_lt_50 | 1054 (87.9) | 518 (85.1) | 269 (88.5) | 189 (91.3) | 78 (98.7) | 0.0013 |
CK_MB1_ge_50 | 145 (12.1) | 91 (14.9) | 35 (11.5) | 18 (8.7) | 1 (1.3) | 0.0013 |
CR_1 | 108.4 (124.7) 66 (51, 117) | 108 (108.2) 67 (51, 123) | 109 (123.1) 66 (49.5, 117) | 114.4 (152.9) 66 (52, 105.5) | 92.6 (163.1) 60.7 (51.4, 81.6) | 0.4877 |
CR_1_lt_150 | 985 (82.2) | 492 (80.8) | 251 (82.6) | 168 (81.2) | 74 (93.7) | 0.0441 |
CR_1_ge_150 | 214 (17.8) | 117 (19.2) | 53 (17.4) | 39 (18.8) | 5 (6.3) | 0.0441 |
DBiL1 | 10.2 (22.3) 5.1 (3.4, 7.7) | 11 (23.5) 5.1 (3.6, 7.8) | 9.1 (14.1) 5.4 (3.5, 8.1) | 11.2 (30.7) 4.8 (3.3, 6.8) | 6.4 (6.3) 4 (2.9, 6.1) | 0.0033 |
DBiL1_lt_20 | 1080 (90.1) | 541 (88.8) | 277 (91.1) | 188 (90.8) | 74 (93.7) | 0.4418 |
DBiL1_ge_20 | 119 (9.9) | 68 (11.2) | 27 (8.9) | 19 (9.2) | 5 (6.3) | 0.4418 |
GGT1 | 50.7 (95.8) 21 (14, 47.8) | 50.6 (101.3) 19 (13.4, 37.3) | 43.4 (74.1) 18.5 (13.4, 40) | 56 (119.1) 23.9 (14, 50) | 65.6 (42.1) 61.4 (47, 79.2) | < 0.0001 |
GGT1_lt_150 | 1134 (94.6) | 569 (93.4) | 291 (95.7) | 196 (94.7) | 78 (98.7) | 0.1714 |
GGT1_ge_150 | 65 (5.4) | 40 (6.6) | 13 (4.3) | 11 (5.3) | 1 (1.3) | 0.1714 |
MPV | 9.2 (3.6) 8.9 (8, 9.9) | 9.1 (1.5) 9 (8.1, 9.8) | 9.2 (1.6) 8.9 (8, 10.2) | 9.6 (8.1) 8.6 (7.9, 9.7) | 9.2 (1.1) 9.2 (8.3, 9.9) | 0.0487 |
MPV_lt_10d5 | 1004 (83.7) | 518 (85.1) | 238 (78.3) | 179 (86.5) | 69 (87.3) | 0.0256 |
MPV_ge_10d5 | 195 (16.3) | 91 (14.9) | 66 (21.7) | 28 (13.5) | 10 (12.7) | 0.0256 |
N1 | 83.8 (13.4) 88.9 (79.3, 92.5) | 84.3 (13.2) 89.2 (80.2, 92.6) | 84.3 (13.8) 89.5 (81.1, 92.6) | 82.7 (13.7) 87.9 (76.2, 92.7) | 81 (11.1) 84.1 (74.2, 89) | 0.0007 |
N1_lt_80 | 310 (25.9) | 149 (24.5) | 68 (22.4) | 60 (29.0) | 33 (41.8) | 0.0029 |
N1_ge_80 | 889 (74.1) | 460 (75.5) | 236 (77.6) | 147 (71.0) | 46 (58.2) | 0.0029 |
PCT | 0.2 (0.1) 0.2 (0.1, 0.2) | 0.1 (0.1) 0.1 (0.1, 0.2) | 0.1 (0.1) 0.1 (0.1, 0.2) | 0.2 (0.1) 0.2 (0.1, 0.2) | 0.1 (0.1) 0.1 (0.1, 0.2) | < 0.0001 |
PCT_lt_0d2 | 903 (75.3) | 483 (79.3) | 240 (78.9) | 119 (57.5) | 61 (77.2) | < 0.0001 |
PCT_ge_0d2 | 296 (24.7) | 126 (20.7) | 64 (21.1) | 88 (42.5) | 18 (22.8) | < 0.0001 |
PLT | 179.4 (90) 172 (113, 236) | 173.6 (87.7) 165 (109, 226) | 170.2 (90.5) 157 (107, 218) | 218.4 (88) 211 (167, 271) | 158.1 (84) 161 (80, 220) | < 0.0001 |
PLT_lt_80 | 155 (12.9) | 79 (13.0) | 49 (16.1) | 11 (5.3) | 16 (20.3) | 0.0006 |
PLT_ge_80 | 1044 (87.1) | 530 (87.0) | 255 (83.9) | 196 (94.7) | 63 (79.7) | 0.0006 |
WBC1 | 14.1 (8) 11.8 (8.6, 17.3) | 14.4 (8.4) 11.9 (8.6, 18.5) | 14.4 (7.9) 12.4 (9.2, 17.7) | 13.2 (7.1) 11.1 (8.3, 16.5) | 12.3 (6.5) 10.6 (8.3, 14.4) | 0.0373 |
WBC1_lt_20 | 979 (81.7) | 484 (79.5) | 250 (82.2) | 173 (83.6) | 72 (91.1) | 0.0642 |
WBC1_ge_20 | 220 (18.3) | 125 (20.5) | 54 (17.8) | 34 (16.4) | 7 (8.9) | 0.0642 |
279 (151) | 289.4 (102.8) | 310.8 (165.4) | 356.2 (253.3) | 219.3 (58.1) | ||
LDH1 | 236.1 (205, 299.3) | 273.3 (218.4, 333) | 259.7 (235.5, 320.5) | 265.1 (221.7, 363.3) | 209.6 (182.8, 234.8) | < 0.0001 |
LDH1_lt_240 | 1101 (91.8) | 579 (95.1) | 277 (91.1) | 184 (88.9) | 61 (77.2) | < 0.0001 |
LDH1_ge_240 | 98 (8.2) | 30 (4.9) | 27 (8.9) | 23 (11.1) | 18 (22.8) | < 0.0001 |
Ingestion_volume | 61.1 (67.5) 40 (20, 80) | 65.1 (69.9) 40 (20, 100) | 55.8 (63.4) 30 (15, 80) | 61.5 (72) 30 (15, 80) | 49.8 (47.3) 40 (20, 60) | 0.2922 |
Ingestion_volume_lt_100 | 927 (77.3) | 452 (74.2) | 244 (80.3) | 161 (77.8) | 70 (88.6) | 0.0141 |
Ingestion_volume_ge_100 | 272 (22.7) | 157 (25.8) | 60 (19.7) | 46 (22.2) | 9 (11.4) | 0.0141 |
LOS | 7.3 (6.8) 5 (2, 11) | 7.4 (7) 5 (2, 10) | 7.9 (6.9) 6 (2, 11.5) | 6.9 (6.1) 5.1 (2, 10.7) | 5.5 (5.8) 3 (1, 8) | 0.0045 |
