Table 2 Sensitivity and specificity analysis comparing the three classifiers in the Puerta de Hierro (PdH) and HMRN cohorts.
From: Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma
Sensitivity/specificity (%) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
MCD2-S | BN22-S | EZB2-S | ST22-S | N12-S | ||||||
PdH cohort | ||||||||||
Two-step versus LymphGen | 100 | 89.7 | 81.8 | 88.0 | 100 | 86.8 | 50 | 91.4 | – | 94.1 |
Two-step versus AIC cluster | 97.5 | 92.0 | 41.2 | 97.2 | 88.5 | 90.6 | 56.1 | 95.8 | – | – |
HMRN cohort | ||||||||||
Two-step versus LymphGen | 98.5 | 90.1 | 64.0 | 95.8 | 89.9 | 92.8 | 81.3 | 92.7 | 100 | 99.8 |
LymphGen versus AIC cluster | 81.3 | 99.6 | 39.2 | 97.8 | 84.9 | 93.5 | 50.4 | 99.0 | – | – |
