Figure 3
From: Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord
Sulf2a depletion impairs OPC development. Side views of 48 hpf embryos. (a-f) Detection (a–e) and quantification (f) of OPCs by immunodetection of Sox10 (green in a–c, red in d,e) in Tg(olig2:DsRed) embryos (red in a–c) injected with ctrlMO (a, n = 73), sulf2aMOATG (b, n = 31) or sulf2aMOsplice (c, n = 47) and wild-type (d, n = 10) or sulf2a−/− (e, n = 48) Tg(olig2:GFP) embryos (green in d,e) from 9 and 6 independent experiments, respectively. Datasets were compared with Mann Whitney’s test (two-tailed). Data are presented as mean number of cells per embryo ± s.d (*p < 0.05, ****p < 0.0001).
