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Figure 1

From: Fetal bovine serum albumin inhibits antimicrobial peptide activity and binds drug only in complex with α1-antitrypsin

Figure 1

Susceptibility of antimicrobials to serum inhibition. (a) Effect of fetal bovine serum on the antimicrobial activity of TP4 to E. coli (left), Staphylococcus aureus (middle) bacteria and Candida albicans (right). (b) The band shift of TP4 caused by fetal bovine serum. (c, d) Effect of fetal bovine serum on the antimicrobial activities of cationic antimicrobial peptides and TP4 mutants to E. coli (top or left panel) and band shift of antimicrobials (4 μg each) caused by serum (bottom or right panel). PBS, phosphate-buffered saline; 5% FBS, 5% (v/v) fetal bovine serum in PBS.

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