Figure 3 | Scientific Reports

Figure 3

From: Positive-charge tuned gelatin hydrogel-siSPARC injectable for siRNA anti-scarring therapy in post glaucoma filtration surgery

Figure 3

SPARC expression of C57Bl6/J MTFs at day (a) 2 and (b) 7 when treated with siSPARC-loaded Gtn-Tyr hydrogel with different surface charges. (c) Gene expression of SMA, Col 1a1, fibronectin, MMP2 and MMP4; and (d) SPARC and Col 1a1 protein expression of C57 MTFs after being treated with optimal hydrogel formulation (F2) at day 7. * denote P < 0.05, ** denote P < 0.01, *** denote P < 0.001 and **** denote P < 0.0001.

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