Figure 5

Enterotype grouping, Bifidobacterium abundance and functional gene annotation. (A) Enterotype analysis of samples at the family level. Samples clustered in three different enterotypes reported by different colors. In the center of the cluster is shown the main bacterial family responsible for the enterotype formation. (B) Bacterial families driving enterotype formation. Longer arrows indicate a stronger contribution. (C) Quantification of total Bifidobacterium spp. by enterotype. (D) Abundance of ARGs in all samples grouped by enterotype. (E) Heatmap showing relative abundance and functional annotation of KEGG orthologous genes related to HMO-utilization across enterotypes.