Table 1 The IC50 (µg/ml) value of MYG, E-guggulsterone, Z-guggulsterone and positive control.

From: CYP3A4 mediated pharmacokinetics drug interaction potential of Maha-Yogaraj Gugglu and E, Z guggulsterone

Test samples

CYP3A4

IC50 (µg/ml)

MYG

11.43 ± 2.12*

E-guggulsterone

03.96 ± 1.04

Z-guggulsterone

24.08 ± 0.48**

Ketoconazole

01.74 ± 0.66

  1. Level of significance at *P < 0.05, **P < 0.01.
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