Figure 6
From: CircRNA_103765 acts as a proinflammatory factor via sponging miR-30 family in Crohn’s disease
CircRNA_103765 promotes human intestinal epithelial cells proliferation and apoptosis through circRNA_103765/miR-30/DLL4 axis. (A,D) The cell proliferation was determined after transfection with indicated vectors, mimics or inhibitors at the indicated days. (B,C,E,F) Apoptosis rate was analysed by flow cytometry after transfection. (G–L) Relative expression of DLL4 and downstream cell cycle-related molecules and apoptosis-related molecules at protein level in cells transfected with indicated vectors, mimics or inhibitors was determined by western blot. (M) Schematic diagram of how circRNA_103765 sponge miR-30 mediated DLL4 expression. *P < 0.05.
