Figure 3

The effect of Mlig-TIM29(RNAi) on morphology and regeneration. (a) After 4 weeks of RNAi treatment, most Mlig-TIM29(RNAi) worms (> 95%) look similar to the gfp(RNAi) controls. A few individuals, however, demonstrate a decreased capacity of tissue turnover. This is illustrated by the worm on the right, which shrank, degenerated the gonads, and developed bulges in the epidermis. (b) During knockdown of Mlig-TIM29 worms are not able to regenerate the body. Post Amp. represents time after amputation of the body. All scale bars are 100 µm.