Table 2 Univariate and multivariate logistic regression analyses of factors influencing controlled attenuation parameter values in patients with CHB.

From: Effect of silibinin capsules combined with lifestyle modification on hepatic steatosis in patients with chronic hepatitis B

 

S0 (n = 3911)

 ≥ S1 (n = 1769)

Univariate, OR (95% CI)

P

Multivariate, OR (95% CI)

P

Age, years

42.21 ± 11.5

43.42 ± 10.4

1.010 (1.005–1.015)

< 0.001

  

Male patients, n (%)

2651 (68.8)

1422 (80.5)

1.962 (1.713–2.246)

< 0.001

  

BMI, kg/m2

22.78 ± 2.8

24.28 ± 3.5

1.218 (1.194–1.243)

< 0.001

1.142 (1.057–1.234)

0.001

Waist circumference, cm

80.14 ± 7.9

85.56 ± 8.5

1.085 (1.077–1.094)

< 0.001

  

Hip circumference, cm

92.47 ± 6.3

96.67 ± 22.8

1.099 (1.088–1.110)

< 0.001

  

ALT, U/L

31 (21–47)

39 (28–57)

1.009 (1.007–1.011)

< 0.001

1.011 (1.006–1.017)

< 0.001

AST, U/L

31 (25–42)

33 (26–42)

1.001 (0.998–1.003)

0.629

  

GLU

5.61 ± 1.8

5.86 ± 3.5

1.027 (0.980–1.076)

0.269

  

TG, mmol/L

1.16 ± 1.0

1.63 ± 1.1

1.736 (1.526–1.975)

< 0.001

1.537 (1.255–1.881)

< 0.001

Cholesterol, mmol/L

4.21 ± 1.2

4.63 ± 4.1

1.185 (1.081–1.299)

< 0.001

  

HDL-C, mmol/L

1.43 ± 0.46

1.41 ± 3.3

0.436 (0.341–0.558)

< 0.001

  

LDL-C, mmol/L

2.34 ± 0.75

2.62 ± 1.1

1.522 (1.333–1.737)

< 0.001

1.887 (1.172–3.034)

0.011

ALB, g/L

45.86 ± 5.5

46.00 ± 5.1

1.005 (0.993–1.018)

0.427

  

GLB, g/L

30.47 ± 6.8

30.78 ± 7.2

1.006 (0.997–1.016)

0.182

  

TB, μmol/L

18.20 ± 11.9

18.09 ± 14.2

0.999 (0.994–1.005)

0.797

  

DB, μmol/L

6.34 ± 7.0

5.67 ± 4.7

0.977 (0.963–0.992)

0.003

  

GGT, U/L

24 (16–41)

28 (18–50)

1.003 (1.002–1.005)

< 0.001

  

ALP, U/L

78( 63–97)

79 (64–97)

1.001 (0.999–1.003)

0.350

  

Platelet × 109/L

118 (79–162)

124 (84–167)

1.002 (1.000–1.003)

0.035

1.003 (1.000–1.017)

0.023

LSM, kPa

10.16 ± 8.3

9.70 ± 7.3

0.992 (0.985–1.000)

< 0.001

  
  1. BMI body mass index, ALT alanine aminotransferase, AST aspartate aminotransferase, TB total bilirubin, DB direct bilirubin, TG triacylglycerol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, GGT gamma glutamyltransferase, ALP alkaline phosphatase, LSM liver stiffness measurement, CAP controlled attenuation parameter.