Figure 5
From: Gene expression and functional abnormalities in XX/Sry Leydig cells
Altered expression of genes normally enriched in ALCs. (a) Expression of Agt, Hmgcs2, Lcn2, Sepp1 and Ptgds in XY adult testes was examined using in situ hybridization. Scale bars = 100 μm. (b) Expression of genes that are normally enriched in ALCs in XY and XX/Sry ALCs was obtained from the transcriptome datasets. The displayed CPMs are the means of biological triplicates. Increased and decreased gene expression in the XX/Sry ALCs is indicated in red and blue, respectively, with deeper shading for larger differences.
