Table 2 Association analysis and univariate analysis for logarithm 10 levels of IL-8 among colorectal cancer patients.
From: A prognostic model for colorectal cancer based on CEA and a 48-multiplex serum biomarker panel
Association analyses (Mann–Whitney U or Kruskall–Wallis test) | Univariate hazard ratio for disease-specific survival3 | ||||||
|---|---|---|---|---|---|---|---|
Median value (pg/ml) | IQR | p value1 | HR | 95% CI | p value4 | ||
Gender | |||||||
Female | 43 | 32–64 | 0.802 | 1.67 | 0.96–2.9 | 0.067 | |
Male | 46 | 33–60 | 2.39 | 1.42–4.02 | 0.001 | ||
Age | |||||||
≤ 67 | 46 | 35–63 | 0.221 | 1.86 | 1.05–3.28 | 0.033 | |
> 67 | 42 | 32–59 | 2.37 | 1.42–3.95 | 0.001 | ||
Stage | Stage groups | ||||||
I | 37 | 28–47 | < 0.0012 | I–II | 1.02 | 0.34–3.11 | 0.968 |
II | 43 | 35–57 | III–IV | 1.67 | 1.11–2.53 | 0.015 | |
III | 40 | 31–61 | |||||
IV | 60 | 45–110 | |||||
Histology | |||||||
Non-mucinous | 43 | 33–60 | 0.800 | 1.85 | 1.24–2.75 | 0.003 | |
Mucinous | 45 | 31–76 | 7.76 | 1.57–38.3 | 0.012 | ||
Side | |||||||
Right | 49.46 | 37–68 | 0.005 | 2.34 | 0.99–5.52 | 0.052 | |
Left | 41.62 | 31–58 | 2.29 | 1.48–3.55 | < 0.001 | ||
Location | |||||||
Colon | 49 | 35–66 | 0.005 | 2.19 | 1.23–3.88 | 0.008 | |
Rectum | 41 | 31–57 | 2.23 | 1.31–3.80 | 0.003 | ||