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Figure 1

From: Effect of SSRI exposure on the proliferation rate and glucose uptake in breast and ovary cancer cell lines

Figure 1

SSRI treatment or 5-HT exposure marginally impact cell proliferation of breast cancer cell lines. Bar graphs depict relative proliferation assessed by Fluoroskan of MCF-10A (a), MCF-7 (b), MDA-MB-231 (c), MDA-MSC-hyb1 (d) and MDA- MSC-hyb3 (e) cells in response to treatment with 10 nM, 100 nM or 1000 nM fluoxetine (Fluo; yellow), sertraline (Sert; red), citalopram (Cita; blue) or 5-HT (grey) for indicated time periods normalized to DMSO-treated control cells (Ctrl; white). Data are depicted as mean ± SEM and summarize n = 9–10 (Ctrl) and at least n = 3 (SSRI/5-HT) experiments. P-values were determined by two-way ANOVA followed by Dunnett’s multiple comparison test; ***P < 0.001; **P < 0.01; *P < 0.05 versus corresponding Ctrl.

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