Figure 4 | Scientific Reports

Figure 4

From: Combination therapy of cisplatin with cilastatin enables an increased dose of cisplatin, enhancing its antitumor effect by suppression of nephrotoxicity

Figure 4

Antitumor effects of cisplatin combined with cilastatin. BALB/cA mice were inoculated s.c. with CT26 tumor cells (A), and SCID mice were injected s.c. with A549 tumor cells (B). The mice were treated with 3 mg/kg or 6 mg/kg cisplatin i.p. on days 6, 9 and 12 with or without administration of cilastatin s.c. from days 6 to 12.

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