Figure 3

Histopathological observations of the heart (200 ×). (A) Control rat heart revealed normal architecture of myocardium. (B) The I/R model rats showedfragmentation of heart myofibrils, necrosis, vacuolar degeneration, loss of striations, hyperemia, and inflammatory infiltration. (C) GZ-treated rats showed inflammatory infiltration. (D) GZ + RDK-treated rats showedpartly vacuolar degeneration, fragmentation of heart myofibrils, loss of striations, (E) SWTX-treated rats showedwider gaps between myocardial fibers, no inflammatory infiltration. n = 3 in each group.