Table 1 Mean test and train accuracies for prediction of protein–protein interaction interfaces.
PPI category | FNAT | |||||||
|---|---|---|---|---|---|---|---|---|
NC > 0.80; NNC ≤ 0.25 | NC > 0.80; NNC < 0.25 and ≤ 0.5 | NC > 0.80; NNC < 0.50 and ≤ 0.80 | NC > 0.80; NNC ≤ 0.80 | |||||
Mean test accuracy (%) | Mean test AUC | Mean test accuracy (%) | Mean test AUC | Mean test accuracy (%) | Mean test AUC | Mean test accuracy (%) | Mean test AUC | |
Homo | 99.28 ± 0.41 | 0.99 ± 0.00 | 98.78 ± 0.51 | 0.99 ± 0.00 | 97.50 ± 0.60 | 0.99 ± 0.00 | 98.52 ± 0.50 | 0.99 ± 0.00 |
Hetero | 99.04 ± 0.49 | 0.99 ± 0.00 | 98.31 ± 0.71 | 0.99 ± 0.00 | 96.93 ± 0.961 | 0.99 ± 0.00 | 98.05 ± 0.55 | 0.99 ± 0.00 |
PPI category | iRMSD | |||||||
|---|---|---|---|---|---|---|---|---|
NC < 5 Å; NNC ≥ 15 Å | NC < 5 Å; NNC ≥ 10 Å and < 15 Å | NC < 5 Å; NNC ≥ 5 Å and < 10 Å | NC < 5 Å; NNC ≥ 5 Å | |||||
Mean test accuracy (%) | Mean test AUC | Mean test accuracy (%) | Mean test AUC | Mean test accuracy (%) | Mean test AUC | Mean test accuracy (%) | Mean test AUC | |
Homo | 97.55 ± 1.34 | 0.99 ± 0.00 | 97.12 ± 1.15 | 0.99 ± 0.00 | 94.90647 ± 1.14 | 0.98 ± 0.00 | 97.00 ± 0.92 | 0.99 ± 0.00 |
Hetero | 96.66 ± 0.87 | 0.99 ± 0.00 | 96.82 ± 0.59 | 0.99 ± 0.00 | 96.83 ± 0.65 | 0.99 ± 0.00 | 97.37 ± 0.53 | 0.99 ± 0.00 |