Figure 5

Percentage of pre-S2 plus pre-S1 + pre-S2 deletion was positively correlated with the density of CD4⁺CD25⁺ cells and Foxp3-expressing cells but negatively with granzyme B-expressing cells in HCC tissues. (A) Correlation between the percentage of pre-S2 plus pre-S1 + pre-S2 deletion and the density of CD4⁺CD25⁺ cells in HCC tissues. (B) Correlation between the percentage of pre-S2 plus pre-S1 + pre-S2 deletion and the density of Foxp3-expressing cells in HCC tissues. (C) Correlation between the percentage of pre-S2 plus pre-S1 + pre-S2 deletion and the density of granzyme B-expressing cells in HCC tissues. (D) Correlation between the density of CD4⁺CD25⁺ cells and Foxp3-expressing cells in HCC tissues. (E) Correlation between the density of CD4⁺CD25⁺ cells and granzyme B-expressing cells in HCC tissues. (F) Correlation between the density of Foxp3- and granzyme B-expressing cells in HCC tissues. The associated linear regression line was depicted in 40 HBV-related HCC patients in each graph. A P value < 0.05 was considered statistically significant.