Table 2 Percentage average IOP reduction for responder and non-responder genotype frequencies for MLIP.

From: MLIP genotype as a predictor of pharmacological response in primary open-angle glaucoma and ocular hypertension

MLIP

BL group

PG group

NR group

Total n (%)

56 (29.5%)

58 (31.7%)

21 (9.0%)

A/A

2 (23.3%)

9 (33.8%)

1 (0.0%)

A/B

21 (30.5%)

29 (30.2%)

13 (10.2%)

B/B

33 (29.3%)

20 (32.8%)

7 (7.9%)

  1. MLIP, muscular LMNA interacting protein; A, 1 copy allele; B, no copies allele; BL, beta-blocker (timolol maleate) treatment group; PG, prostaglandin analogue (latanoprost) treatment group; NR, patients not responsive for any treatment in monotherapy; n, number of individuals; (%), percentage average IOP reduction.