Table 1 Clinical characteristics of the study population and of groups defined by TG/HDL-C quartiles. [Continuous variables are presented as mean ± standard deviation, categorical variables as absolute N and (%); * = P value only for comparison of Quartile IV vs. Quartile I].
Study population n = 355 | Quartile I < 1.305 n = 89 | Quartile II 1.305–2.095 n = 89 | Quartile III 2.129–3.384 n = 88 | Quartile IV > 3.384 n = 89 | P value for trend | |
|---|---|---|---|---|---|---|
Demographics | ||||||
Age, years | 60 ± 9 | 60 ± 8 | 61 ± 9 | 61 ± 9 | 59 ± 9 | ns |
Male gender | 211 (59) | 35 (39) | 47 (53) | 61 (69) | 68 (76) | < 0.0001 |
Clinical characteristics | ||||||
Typical angina | 87 (25) | 21 (23) | 26 (29) | 18 (21) | 22 (25) | ns |
Atypical angina | 213 (60) | 55 (62) | 53 (60) | 53 (60) | 52 (58) | |
Non-anginal chest pain | 55 (15) | 13 (15) | 10 (11) | 17 (19) | 15 (17) | |
LVEF% | 60 ± 8 | 61 ± 8 | 61 ± 8 | 60 ± 9 | 59 ± 9 | ns |
Cardiovascular risk factors | ||||||
Family history of CAD | 118 (33) | 26 (29) | 31 (35) | 31 (35) | 30 (34) | ns |
Diabetes | 112 (31) | 18 (20) | 20 (22) | 32 (36) | 42 (48) | 0.0002 |
Hypercholesterolemia | 216 (61) | 50 (56) | 55 (62) | 56 (64) | 55 (62) | ns |
Hypertension | 266 (64) | 54 (61) | 61 (69) | 54 (61) | 57 (65) | ns |
Smoking | 78 (22) | 13 (15) | 19 (21) | 18 (20) | 28 (31) | 0.0076* |
BMI, kg/m2 | 27.7 ± 4.1 | 26.2 ± 3.6 | 27.3 ± 3.8 | 28.3 ± 4.5 | 29.1 ± 3.9 | < 0.0001 |
Metabolic syndrome | 118 (33) | 7 (8) | 16 (18) | 29 (33) | 66 (74) | < 0.0001 |
Medications | ||||||
Beta-blockers | 141 (40) | 35 (39) | 32 (36) | 28 (32) | 46 (52) | 0.0430 |
Calcium channel blockers | 47 (13) | 9 (10) | 15 (17) | 12 (13) | 11 (12) | ns |
ACE inhibitors | 112 (32) | 25 (28) | 24 (27) | 27 (31) | 36 (40) | ns |
ARBs | 55 (15) | 12 (13) | 21 (24) | 11 (12) | 11 (12) | ns |
Diuretics | 60 (17) | 4 (4) | 19 (21) | 14 (16) | 23 (26) | 0.0011 |
Anti-diabetic | 72 (20) | 11 (12) | 15 (17) | 17 (19) | 29 (33) | 0.0059 |
Statins | 192 (54) | 46 (52) | 47 (53) | 47 (53) | 52 (58) | ns |
Aspirin | 221 (62) | 51 (57) | 57 (64) | 53 (60) | 60 (67) | ns |
Anti-coagulants | 6 (2) | 2 (2) | 1 (1) | 0 (0) | 3 (3) | ns |
