Table 3 Clinical course and treatment received with IV antibiotics for pediatric patients admitted with severe sepsis in AGH, November 2018-August 2020.
Characteristic | Overall (n = 234) | ITFC ward (n = 77) | Pediatric and isolation (n = 148) | p-value | |||
|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | ||
Mean IV line duration (days, SD¥) | 4.65 (4.37) | 5.25 (4.85) | 4.16 (3.28) | 0.2** | |||
Median IV line duration (IQR¥¥) | 4 (2–6) | 4 (2–6) | 3 (2–6) | ||||
Reasons for IV removal | |||||||
Discharged | 116 | 50 | 27 | 35 | 84 | 57 | 0.004*** |
Died | 75 | 32 | 33 | 43 | 39 | 26 | |
LAMA¥¥¥ | 14 | 6.0 | 3 | 3.9 | 11 | 7.4 | |
Thrombosis | 13 | 5.6 | 7 | 9,1 | 6 | 4.1 | |
Changed to oral medication | 10 | 4.3 | 6 | 7.8 | 3 | 2.0 | |
Transferred | 3 | 1.3 | 1 | 1.3 | 2 | 1.4 | |
Other | 3 | 1.3 | 0 | 3 | 2.0 | ||
Missing | |||||||
IV Antibiotics received | |||||||
Ceftriaxone | 229 | 98 | 76 | 99 | 144 | 97 | 0.7*** |
Cloxacillin | 109 | 47 | 52 | 68 | 53 | 36 | < 0.001* |
Gentamycin | 27 | 12 | 12 | 16 | 13 | 8.8 | 0.2* |
Metronidazole | 27 | 12 | 10 | 13 | 16 | 11 | 0.8* |
Ampicillin | 5 | 2.1 | 0 | 0 | 5 | 3.4 | 0.2*** |
Amoxiclav | 3 | 1.3 | 3 | 3.9 | 0 | 0 | 0.039*** |
Ciprofloxacin | 2 | 0.9 | 1 | 1.3 | 1 | 0.7 | 1.0*** |
Clindamycin | 4 | 1.7 | 3 | 3.9 | 1 | 0.7 | 0.12*** |
Cefazolin | 1 | 0.4 | 0 | 0 | 1 | 0.7 | 1.0*** |
Total IV antibiotics received | |||||||
0 | 2 | 0.9 | 1 | 1.3 | 1 | 0.7 | < 0.001*** |
1 | 99 | 42 | 17 | 22 | 78 | 53 | |
2 | 100 | 43 | 42 | 55 | 55 | 37 | |
3 | 26 | 11 | 14 | 18 | 10 | 6.8 | |
4 | 7 | 3.0 | 3 | 3.9 | 4 | 2.7 | |
Treatment received | |||||||
Appropriate | 169 | 72 | 47 | 61 | 116 | 78 | 0.010*** |
Not appropriate | 53 | 23 | 26 | 34 | 24 | 16 | |
Cannot be assessed | 12 | 5.1 | 4 | 5.2 | 8 | 5.4 | |
