Table 5 Mortality rate and factors associated with death in pediatric patients admitted with severe sepsis in AGH in univariable and multivariable Poisson regression, November 2018–August 2020.

Characteristic	Deaths (n)	Days In hospital	Mortality rate per 1000 person days		Univariable			Multivariable
Characteristic	Deaths (n)	Days In hospital	Rate	CI95%*	iRR**	CI95%	p-value	aiRR***	CI95%	p-value
Sex^¥
Female	49	587.6	83.4	63.0–114.4
Male	32	623.8	51.3	31.1–67.6	0.6	0.4–1.0	0.04	0.7	0.5–1.0	0.08
Age group^¥
0–2	62	909.9	68.1	52.7–90.2	0.7	0.4–1.6	0.2	0.6	0.3–1.3	0.06
3–4	9	232.1	38.8	23.5–82.1	0.4	0.2–1.1		0.4	0.2–0.9
5 and over	8	85.4	93.7	32.2–162.4	Ref			Ref
Ward^¥
ITFC	38	491.3	77.3	54.9–108.7	Ref		0.2	Ref
Pediatric/isolation	41	736.1	55.7	39.9–77.2	0.7	0.5–1.2	0.2	0.8	0.5–1.3	0.4
Malaria RDT^¥
Negative	33	583.4	56.6	34.6–73.9
Positive	49	644.0	76.1	57.4–105.3	1.4	0.9–2.2	0.2	1.4	1.0–2.2	0.09
Suspected measles
No	74	1136.2	65.1	49.0–80.8
Yes	8	91.2	87.7	37.1–163.5	1.4	0.6–2.8	0.3
Sepsis focus
Other	7	108.1	64.8	30.2–135.1	Ref		0.6
CNS	6	169.0	35.5	18.3–84.0	0.5	0.2–1.7
GI tract	18	241.5	74.5	49.2–137.0	1.1	0.5–2.8
Respiratory	33	466.4	70.8	40.7–87.9	1.0	0.5–2.5
Unknown	18	227.4	79.2	46.8–126.0	1.2	0.5–3.0
Severity
Low	27	456.1	59.2	42.5–87.8	Ref		0.9
Moderate	12	196.2	61.2	37.3–109.3	1.0	0.7–2.0
High	25	352.8	70.9	46.1–99.2	1.1	0.5–2.0
Confirmed BSI
No	66	1007.4	65.5	46.4–79.3	Ref
Yes	16	220.0	72.7	49.0–136.5	1.1	0.6–1.9	0.8
Treatment received^¥
Appropriate	54	749.9	72.0	47.9–87.1	1.4	0.9–2.5	0.2	1.5	0.9–2.3	0.1
Inappropriate	19	383.4	49.6	32.8–86.7	Ref
Unable to be assessed	9	94.1	95.6	49.6–178.6	2.0	0.9–4.4		2.0	0.9–4.0

^¥Included in multivariable regression model, *95% Confidence Interval, **Incidence Rate Ratio, ***Adjusted incidence Rate Ratio

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