Table 2 Relationships between clinicopathological factors and upper urinary tract recurrence after TURBT in all patients and those with a smoking history.
All Pts | Pts with a smoking history | |||||||
|---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | |||||
HR (95%CI) | P value | HR (95%CI) | P value | HR (95%CI) | P value | HR (95%CI) | P value | |
Age | 0.255 | 0.252 | ||||||
< 70 years | Ref | Ref | ||||||
≥ 70 years | 1.43 (0.77–2.63) | 1.51 (0.70–3.26) | ||||||
Sex | 0.762 | 0.793 | ||||||
Male | Ref | Ref | ||||||
Female | 1.13 (0.52–2.43) | 1.21 (0.29–5.13) | ||||||
Smoking history | 0.632 | |||||||
Negative | Ref | |||||||
Positive | 1.16 (0.63–2.17) | |||||||
Grade | 0.379 | 0.435 | ||||||
G1–2 | Ref | Ref | ||||||
G3 | 1.31 (0.72–2.39) | 1.35 (0.63–2.89) | ||||||
pT stage | 0.876 | 0.780 | ||||||
Ta | Ref | Ref | ||||||
T1 | 0.95 (0.50–1.82) | 1.12 (0.50–2.50) | ||||||
Multiple | 0.219 | 0.798 | ||||||
No | Ref | Ref | ||||||
Yes | 1.47 (0.80–2.70) | 1.10 (0.52–2.33) | ||||||
Concomitant CIS | 0.194 | 0.006 | 0.006 | |||||
No | Ref | Ref | Ref | |||||
Yes | 1.67 (0.77–3.57) | 3.33 (1.41–7.69) | 3.34 (1.41–7.93) | |||||
Chemotherapy | 0.189 | 0.288 | ||||||
No | Ref | Ref | ||||||
Yes | 0.26 (0.04–1.92) | 0.04 (0.00–14.28) | ||||||
BCG | 0.011 | 0.011 | 0.242 | |||||
No | Ref | Ref | Ref | |||||
Yes | 0.44 (0.23–0.83) | 0.43 (0.23–0.83) | 0.63 (0.29–1.37) | |||||
Urinary pH level | 0.072 | 0.008 | 0.008 | |||||
6.0 or greater | Ref | Ref | Ref | |||||
Less than 6 | 1.79 (0.95–3.33) | 3.70 (1.41–10.0) | 3.73 (1.41–9.84) | |||||
