Table 1 Demographic and clinical characteristics between with and without hypoalbuminemia patients underwent craniotomy for brain tumor.
Variables | Non-hypoalbuminemia N = 39 (10.5%) | Hypoalbuminemia N = 333 (89.5%) | P value |
|---|---|---|---|
Age (years, mean ± SD) | 46 ± 13 | 48 ± 13 | 0.311 |
Sex [M, n (%)] | 20 (51.3) | 141 (42.3) | 0.286 |
BMI | 24.9 ± 2.7 | 23.4 ± 3.3 | 0.010 |
Medical history [n (%)] | |||
Hypertension | 5 (12.8) | 57 (17.1) | 0.496 |
Diabetes | 2 (5.1) | 12 (3.6) | 0.636 |
Coronary heart disease | 2 (5.1) | 5 (1.5) | 0.115 |
Viral hepatitis | 1 (2.6) | 11 (3.3) | 0.805 |
History of stroke | 1 (2.6) | 3 (0.9) | 0.341 |
Lifestyle factors [n (%)] | |||
Smoking | 12 (30.8) | 82 (24.6) | 0.403 |
Drinking | 4 (10.3) | 36 (10.8) | 0.916 |
Pathological classification [n (%)] | |||
Meningiomas | 13 (33.3) | 131 (39.3) | 0.288 |
Gliomas | 9 (23.1) | 111 (33.3) | |
Acoustic neuromas | 3 (7.7) | 21 (6.3) | |
Metastatic tumors | 3 (7.7) | 15 (4.5) | |
Others | 11 (28.2) | 55 (16.5) | |
Intraoperative blood loss [(mL, median (IQR)] | 200 (200–300) | 300 (300–500) | < 0.001 |
Intraoperative total input [(mL, median (IQR)] | 2200 (1813–2688) | 2850 (2300–3500) | < 0.001 |
Intraoperative total urine output [(mL, median (IQR)] | 1775 (1400–2500) | 2600 (2015–3350) | < 0.001 |
Operation time [(h, median (IQR)] | 3.8 (2.7–5.0) | 5.0 (4.0–6.0) | < 0.001 |
NICU time [(days, median (IQR)] | 4 (3–5) | 4 (3–5) | 0.068 |
Hospitalization time [(days, median (IQR)] | 21 (17–28) | 21 (18–28) | 0.524 |
Postoperative complications [n (%)] | |||
Pneumonia | – | 18 (5.4) | 0.137 |
Pulmonary imaging abnormalities | 9 (23.1) | 137 (41.1) | 0.029 |
Epilepsy | 3 (7.7) | 10 (3.0) | 0.131 |
Incision infection | – | 3 (0.9) | 0.552 |
Respiratory failure | – | 11 (3.3) | 0.249 |
Renal failure | – | 3 (0.9) | 0.552 |
Hydrocephalus | – | 3 (0.9) | 0.552 |
Deep vein thrombosis | – | 2 (0.6) | 0.627 |
