Table 4 Comparison of quantitative results of serum metabolic signatures of cholesterol between non-SGA and SGA groups.

From: Maternal dyslipidemia and altered cholesterol metabolism in early pregnancy as a risk factor for small for gestational age neonates

 

Non-SGA (n = 56)

SGA (n = 56)

p-value*

Cholesterol, μg/mL

683.5 (545.2–807.9)

651.1 (554.0–806.6)

0.787

Sitosterol, μg/mL

0.8 (0.6–1.2)

0.9 (0.6–1.2)

0.753

Campesterol, μg/mL

0.9 (0.7–1.4)

0.9 (0.7–1.3)

0.507

Stigmasterol, μg/mL

0.2 (0.1–0.2)

0.2 (0.1–0.2)

0.458

Desmosterol, ng/mL

48.9 (40.6–54.6)

48.9 (41.8–58.4)

0.422

7-Dehydrocholesterol, ng/mL

66.3 (55.4–78.2)

65.7 (57.2–85.0)

0.569

Lathosterol, ng/mL

339.9 (205.0–498.6)

271.8 (181.7–394.0)

0.345

Lanosterol, ng/mL

65.2 (46.7–89.2)

60.4 (40.1–81.3)

0.399

7α-OHC, ng/mL

23.3 (18.9–32.0)

23.9 (15.8–33.8)

0.887

7β-OHC, ng/mL

14.6 (13.4–16.2)

14.2 (13.2–16.2)

0.845

7-Ketocholesterol, ng/mL

18.0 (14.2–27.5)

14.9 (12.8–23.0)

0.157

27-OHC, ng/mL

11.4 (9.0–15.1)

12.3 (10.0–16.3)

0.23

24-OHC, ng/mL

18.0 (15.4–22.8)

18.2 (14.1–23.3)

0.766

4β-OHC, ng/mL

12.5 (10.1–14.6)

12.1 (9.0–14.7)

0.953

Cholesterol/DES

14.2 (12.7–16.4)

13.4 (11.8–16.2)

0.264

Cholesterol/7-DHC

10.2 (9.2–11.5)

10.1 (8.7–11.6)

0.533

Cholesterol/lathosterol

2.1 (1.5–2.9)

2.7 (1.6–3.7)

0.034

Cholesterol/lanosterol

10.9 (8.4–14.1)

10.8 (8.8–15.6)

0.103

Sitosterol/cholesterol

1.24 (1.0–1.7)

1.4 (1.0–1.8)

0.839

Campesterol/cholesterol

1.4 (1.0–1.8)

1.5 (1.0–1.9)

0.535

Stigmasterol/cholesterol

0.2 (0.2–0.3)

0.3 (0.2–0.3)

0.268

Stigmasterol/lathosterol

0.5 (0.3–0.8)

0.7 (0.4–0.9)

0.102

7α-OHC/cholesterol

3.5 (2.7–5.0)

2.9 (2.2–5.5)

0.572

7β-OHC/cholesterol

2.2 (1.8–2.8)

2.2 (1.7–2.8)

0.896

7-KC/cholesterol

3.1 (1.7–3.9)

2.3 (1.8–3.4)

0.268

27-OHC/cholesterol

1.8 (1.4–2.0)

1.9 (1.5–2.3)

0.118

24-OHC/cholesterol

2.7 (2.2–3.3)

2.6 (2.2–3.1)

0.4

4β-OHC/cholesterol

1.7 (1.2–2.1)

1.7 (1.4–2.0)

0.764

7α-OHC/7β-OHC

164.0 (127.3–202.2)

167.2 (114.5–205.4)

0.873

  1. All values were presented by median (interquartile ranges).
  2. *Independent t-tests and Mann–Whitney U test where appropriate.
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