Figure 3 | Scientific Reports

Figure 3

From: Bioinformatic identification of genomic instability-associated lncRNAs signatures for improving the clinical outcome of cervical cancer by a prognostic model

Figure 3

Establishment of the prognostic model and validation of the genomic instability-derived lncRNA signature (LncSig) for outcome prediction in the training set. (A) 5 lncRNAs for establishment of the prognostic model. (B) Estimates of overall survival of patients with low or high risk predicted by the LncSig in the training set (p < 0.001). (C) Time-dependent ROC curves analysis of the LncSig at 3 years (AUC = 0.783). (D) With increasing LncSig score, LncRNA expression patterns, the distribution of somatic mutation and KRAS expression. (E) The distribution of somatic cumulative mutations in high- and low-risk groups. (F) KRAS, PIK3CA, ARID1A and UBQLN4 expression in the high- and low-risk groups. The red represents the high-risk group, and the blue represents the low-risk group.

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