Table 1 Most prominent unique hits in the crosslinked sample. Grey colored parts are obtained from DSSG crosslinked samples while white parts are obtained from BS3 crosslinked samples. a) Intermolecular crosslink pairs of sample #4 (Complex at approx. 135 kDa). b) Intermolecular crosslink pairs of sample #5 (Complex > 245 kDa). c) Both Inter- and intramolecular crosslinked pairs in the reference sample #3 (DNJ-13 dimer).
From: Nematode CDC-37 and DNJ-13 form complexes and can interact with HSP-90
Peptide 1 | Peptide 2 | Protein 1 | Protein 2 |
|---|---|---|---|
(a) | |||
EAGAENKFK | GTTSKK | DNJ-13 (44) | CDC-37 (60) |
MEQEKIDK | YHPDKNK | CDC-37 (50) | DNJ-13 (35) |
GKDYYKVLGISK | EKGTTSK | DNJ-13 (3) | CDC37 (55) |
KMKITR | KPQAPK | DNJ-13 (179) | CDC-37 (132) |
MEQEKIDK | YHPDKNK | CDC-37 (50) | DNJ-13 (35) |
AYRKMALK | MEELEKK | DNJ-13 (26) | CDC-37 (67) |
MGKDYYK | GTTSKK | DNJ-13 (1) | CDC-37 (60) |
MPIDYSK | GTTKKMK | CDC-37 (1) | DNJ-13 (176) |
AYRKMALK | GTTSKK | DNJ-13 (26) | CDC-37 (60) |
GLPNPKSPSHR | PIDYSK | DNJ-13 (299) | CDC-37 (2) |
KEAELEEK | MGKDYYK | CDC-37 (97) | DNJ-13 (3) |
LERMAEKK | DKPHPK | CDC-37 (44) | DNJ-13 (235) |
(b) | |||
KFEAAEPVYMK | MGKDYYK | CDC-37 (241) | DNJ-13 (1) |
MEQEKIDK | YHPDKNK | CDC-37 (50) | DNJ-13 (35) |
MEELEKKLAAADVTDK | KMALKYHPDK | CDC-37 (67) | DNJ-13 (30) |
MEQEKIDK | YHPDKNK | CDC-37 (50) | DNJ-13 (35) |
(c) | |||
DYYKVLGISK | GATDDEIKK | DNJ-13 (7) | DNJ-13 (21) |
GATDDEIKK | YHPDKNK | DNJ-13 (21) | DNJ-13 (35) |
GLPNPKSPSHR | GATDDEIKK | DNJ-13 (299) | DNJ-13 (21) |
KVMTDNAQR | EAGAENKFK | DNJ-13 (183) | DNJ-13 (44) |
DYYKVLGISK | EAGAENKFK | DNJ-13 (7) | DNJ-13 (44) |
NKEAGAENK | GKDYYK | DNJ-13 (37) | DNJ-13 (3) |
KIYDQFGEEGLK | GATDDEIKK | DNJ-13 (62) | DNJ-13 (21) |
VLGISKGATDDEIKK | EAGAENKFK | DNJ-13 (13) | DNJ-13 (44) |
EIAEAYDVLSDDKKK | KIYDQFGEEGLK | DNJ-13 (59) | DNJ-13 (62) |
VEKISLK | EGSDIKR | DNJ-13 (252) | DNJ-13 (248) |
EAGAENKFK | GATDDEIKK | DNJ-13 (44) | DNJ-13 (21) |
DYYKVLGISK | EGSDIKR | DNJ-13 (7) | DNJ-13 (248) |
