Figure 3

The dose-corrected tacrolimus blood concentrations in heart transplant recipients carrying CYP3A5*3/*3 genotype (A) and CYP3A5*1 allele (B) in a 15-month period after transplantation. The dotted line represents the daily dose of corticosteroid. *P < 0.05, **P < 0.001, ***P < 0.0001.