Table 1 Baseline characteristics of enrolled patients after endoscopic submucosal dissection with curative resection.

From: Risk factor-based optimal endoscopic surveillance intervals after endoscopic submucosal dissection for gastric adenoma

 

Total

(n = 698)

No recurrence

(n = 647)

Recurrence

(n = 51)

P-value*

Age, mean ± SD, years

61.8 ± 10.0

61.5 ± 10.1

66.0 ± 8.7

 < 0.01

Sex, n (%)

   

0.01

Male

498 (71.3)

454 (70.2)

44 (86.3)

 

Female

200 (28.7)

193 (29.8)

7 (13.7)

 

Location, n (%)

   

0.60

Upper third

28 (4.0)

27 (4.2)

1 (2.0)

 

Middle third

256 (36.7)

239 (36.9)

17 (33.3)

 

Lower third

414 (59.3)

381 (58.9)

33 (64.7)

 

Lesion diameter

    

Mean ± SD, mm

17.9 ± 8.3

17.8 ± 8.3

19.4 ± 8.5

0.17

 ≤ 10 mm, n (%)

150 (21.5)

143 (22.1)

7 (13.7)

 

11–20 mm, n (%)

365 (52.3)

338 (52.2)

27 (52.9)

 

21–30 mm, n (%)

137 (19.6)

125 (19.3)

12 (23.5)

 

 > 30 mm, n (%)

46 (6.6)

41 (6.3)

5 (9.8)

 

Gross morphology type, n (%)

   

0.20

Elevated/flat

669 (95.8)

618 (9.5)

51 (100.0)

 

Depressed

29 (4.2)

29 (4.5)

  

Number of lesion, n (%)

    

Single

634 (90.8)

592 (91.5)

42 (82.4)

0.04**

Multiple

64 (9.2)

55 (8.5)

9 (17.6)

 

Atrophy gastritis, n (%)

500 (71.6)

454 (70.2)

46 (90.2)

 < 0.01

Antrum

180 (36.0)

171 (37.7)

9 (19.6)

 

Expanded to the lesser curvature of the body

269 (53.8)

240 (52.9)

29 (63.0)

 

Entire stomach

51 (10.2)

43 (9.4)

8 (17.4)

 

Intestinal metaplasia, n (%)

534 (76.5)

489 (75.6)

45 (88.2)

0.04

Helicobacter pylori infection, n (%)

   

0.95

Current

203 (29.1)

188 (29.1)

15 (29.4)

 

Previous (including eradicated)

167 (23.9)

154 (23.8)

13 (25.5)

 

None

328 (47.0)

301 (46.5)

23 (45.1)

 

Specimen area − lesion areaa, mean ± SD, mm2

2.4 ± 1.4

2.4 ± 1.3

2.7 ± 1.6

0.19

Total procedure time

50.8 ± 32.7

51.2 ± 33.3

46.2 ± 24.6

0.30

Fibrosis during ESD, n (%)

131 (18.8)

127 (19.6)

4 (7.8)

0.04

Presence of ulceration at 1st follow-up, n (%)

17 (2.4)

16 (2.5)

1 (2.0)

0.82

Scar morphology at 1st follow-upb, n (%)

   

 < 0.001

Flat scar

642 (92.0)

602 (93.0)

40 (78.4)

 

Protruded scar

56 (8.0)

45 (7.0)

11 (21.6)

 

Discrepancy, n (%)

   

0.85

Downgrade and concordant

647 (92.8)

600 (92.9)

47 (92.2)

 

Upgrade

50 (7.2)

46 (7.1)

4 (7.8)

 
  1. ESD, endoscopic submucosal dissection; n, number; NA, not applicable; SD, standard deviation.
  2. *Non-recurrence vs. recurrence.
  3. **Fisher’s exact test was applied.
  4. a(Area of the specimen − area of the lesion)/1000.
  5. bIf ulceration was observed at the first follow-up, scar morphology was evaluated according to endoscopy at the 6-month follow-up.
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