Table 3 SARS-CoV-2 IgG seropositivity by self-reported clinical characteristics.

From: SARS-CoV-2 IgG seropositivity in a cohort of 449 non-hospitalized individuals during Spanish COVID-19 lockdown

  

IgG seropositivity

Univariate analysis

Multivariate analysis

%

(95% CI)

OR

95% CI

P-value

OR

95% CI

P-value3

PCR status

Never done

29.28

(24.48–33.99)

1

 

 < 0.0012

1

  

Negative

42.42

(25.48–60.78)

1.78

0.86 to 3.67

1.52

0.53 to 4.33

0.432

Positive

92.31

(63.97–99.81)

29.98

3.72 to 225.50

21.97

1.91 to 252.92

0.013

Contact with

confirmed case

No contact

24.74

(18.42–31.89)

1

 

 < 0.0012

1

  

Household member

48.15

(39.47–56.41)

2.83

1.74 to 4.60

4.26

2.19 to 8.30

 < 0.001

Non-cohabitating

29.86

(22.53–38.04)

1.30

0.79 to 2.14

1.69

0.83 to 3.41

0.146

COVID-19 symptoms

No

14.60

(9.15–21.64)

1

  

1

  

Yes

41.99

(36.45–47.68)

4.29

2.54 to 7.26

 < 0.0011

1.052

0.12 to 85.71

0.982

Type of symptoms

Ageusia/Anosmia

77.36

(68.21–84.92)

13.57

8.02 to 22.96

 < 0.0011

15.30

5.98 to 39.12

 < 0.001

Pneumonia diagn.$

75.00

(47.62–92.73)

6.35

2.01 to 20.03

0.0011

1.84

0.32 to 10.48

0.492

Cutaneous

63.33

(43.86–80.07)

3.76

1.74 to 8.12

 < 0.0011

1.53

0.46 to 5.06

0.483

Fever

47.51

(40.06–55.05)

2.83

1.89 to 4.23

 < 0.0011

1.59

0.75 to 3.36

0.225

GI symptoms

50.47

(40.63–60.23)

2.57

1.65 to 4.02

 < 0.0011

1.44

0.69 to 3.01

0.325

Asthenia

44.51

(36.97–52.24)

2.19

1.47 to 3.27

0.0121

1.52

0.67 to 3.45

0.311

Dyspnea

47.06

(34.83–59.55)

1.96

1.16 to 3.30

0.0041

0.62

0.23 to 1.70

0.355

Cough

42.67

(34.64–50.99)

1.84

1.22 to 2.78

0.0081

0.99

0.47 to 2.10

0.981

Myalgia

42.47

(34.93–50.51)

1.78

1.18 to 2.68

0.0181

0.66

0.30 to 1.47

0.309

Headache

40.46

(33.08–48.18)

1.64

1.10 to 2.44

0.7351

1.02

0.48 to 2.15

0.956

Odynophagia

32.20

(23.90–41.43)

0.92

0.59 to 1.43

 < 0.0011

0.34

0.16 to 0.69

0.003

Number of symptoms

0

14.60

(9.15–21.64)

1

 

 < 0.0012

1

  

1–3

32.59

(24.78–41.19)

2.83

1.56 to 5.13

1.82

0.45 to 71.96

0.751

4–6

38.79

(29.89–48.29)

3.71

2.03 to 6.78

1.55

0.10 to 25.34

0.760

7–9

70.00

(55.39–82.14)

13.65

6.33 to 29.45

2.47

0.27 to 22.31

0.421

 ≥ 10

63.64

(30.79–89.07)

10.24

2.74 to 38.21

7.46

1.74 to 32.03

0.007

  1. $diagnosis.
  2. 1Fisher’s exact test.
  3. 2Chi-square test.
  4. 3Enter multivariate logistic regression. Variables significantly associated with seropositivity are highlighted in bold.
  5. OR, Odds Ratio. 95% CI, 95% Confidence interval. GI, Gastrointestinal.
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