Table 1 The potential urinary protein biomarkers for VILI.

From: Differential urine proteome analysis of a ventilator-induced lung injury rat model by label-free quantitative and parallel reaction monitoring proteomics

Uniprot ID

Protein name

Human ortholog

Trend

Lung diseases biomarkers

P15684

Aminopeptidase N (AMPN)

P15144

BALF13,21, serum22

Q64319

Neutral and basic amino acid transport protein rBAT (SLC31)

Q07837

 

Q64230

Meprin A subunit alpha (MEP1A)

Q16819

 

P28826

Meprin A subunit beta (MEP1B)

Q16820

Urine23

Q63424

Solute carrier family 15 member 2 (S15A2)

Q16348

 

P00697

Lysozyme C-1 (LYSC1)

P61626

BALF13,24, sputum25

Q9JJ19

Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHRF1)

O14745

 

Q99MA2

Xaa-Pro aminopeptidase 2 (XPP2)

O43895

 

P14740

Dipeptidyl peptidase 4 (DPP4)

O70244

Lung tissue26, plasma27

P07314

Glutathione hydrolase 1 proenzyme (GGT1)

P19440

 

Q641X3

Beta-hexosaminidase subunit alpha (HEXA)

P06865

 

P62898

Cytochrome c (CYC)

P99999

Serum28, urine23

P10719

ATP synthase subunit beta (ATPB)

P06576

 
  1. ↑ means up-regulated trend, ↓ means down-regulated trend.