Figure 2 | Scientific Reports

Figure 2

From: Sildenafil improves hippocampal brain injuries and restores neuronal development after neonatal hypoxia–ischemia in male rat pups

Figure 2

Immunostaining for mature neurons in sham and HI rats treated with vehicle or sildenafil. Cells were counted in three regions of the hippocampus: i.e., dentate gyrus (DG), CA1, and CA3 regions of the ipsilateral hippocampus. (A) Representative immunofluorescent micrographs of the mature neurons labeled with NeuN in the ipsilateral DG region of the hippocampus. (B) Mature neuronal cells labeled with NeuN (median with individual data points representation) in DG, CA1 and CA3. Significance: p value from Kruskal–Wallis test, with Dunn’s post-hoc comparison tests: **p < 0.01. Number of animals: n = 7 sham vehicle, 3 HI vehicle, 8 HI 2 mg/kg, 9 HI 10 mg/kg and 8 HI 50 mg/kg.

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