Scientific Reports

Table 3 Multivariate analysis of the association between eGFR slope and individual variables.

From: Comparison of multiparametric magnetic resonance imaging sequences with laboratory parameters for prognosticating renal function in chronic kidney disease

	SPRC	P	Adjusted by
			UPCR		UPCR, + mBP, UA, eGFR, DKD
			SPRC	P	SPRC	P
mBP	− 0.001	0.986
UPCR	− 0.329	< 0.001
UA	0.039	0.640
eGFR	0.035	0.677
DKD	− 0.080	0.332
Cortical T2*	0.179	0.030	0.170	0.030	0.171	0.033
medullary T2*	0.124	0.136	0.118	0.134	0.099	0.223
T2* gradient	− 0.266	0.001	− 0.235	0.002	− 0.270	0.001
Cortical T1	− 0.119	0.141	− 0.069	0.376	− 0.086	0.278
Medullary T1	− 0.065	0.438	− 0.014	0.865	− 0.032	0.697
T1 gradient	0.107	0.191	0.059	0.451	0.065	0.411
Cortical fASL	0.035	0.664	− 0.065	0.414	− 0.032	0.718
Medullary fASL	− 0.048	0.553	− 0.133	0.090	− 0.121	0.153
fASL gradient	− 0.127	0.120	− 0.032	0.696	− 0.080	0.352
Cortical Dixon	0.115	0.165	0.053	0.511	0.055	0.511
Medullary Dixon	0.094	0.252	0.059	0.450	0.057	0.481
Dixon gradient	− 0.230	0.007	− 0.093	0.302	− 0.136	0.186
Cortical ADC	0.180	0.024	0.116	0.134	0.129	0.100
Medullary ADC	0.179	0.025	0.118	0.127	0.124	0.115
ADC gradient	− 0.048	0.550	− 0.002	0.981	− 0.025	0.757
Cortical FA	− 0.082	0.323	− 0.115	0.144	− 0.107	0.176
Medullary FA	0.032	0.694	− 0.038	0.632	− 0.022	0.794
FA gradient	0.129	0.125	0.072	0.375	0.112	0.210

Multivariate analysis was used for the association between eGFR slope and each variable. mBP mean blood pressure, UPCR urinary protein creatinine ratio, UA uric acid, DKD diabetic kidney disease, fASL perfusion volume estimated by arterial spin labelling, Dixon signal intensity of Dixon water image, ADC apparent diffusion coefficients, FA fractional anisotropy, SPRC standardized partial regression coefficients, P value < 0.05 was considered significant (bold). Objective variable: eGFR slope. All results were adjusted for age and gender.

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